View source for 5gzr


==Zika virus E protein complexed with a neutralizing antibody Z23-Fab==
<SX load='5gzr' size='340' side='right' viewer='molstar' caption='[[5gzr]], [[Resolution|resolution]] 9.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5gzr]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Zika_virus Zika virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GZR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GZR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 9.4&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gzr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gzr OCA], [https://pdbe.org/5gzr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gzr RCSB], [https://www.ebi.ac.uk/pdbsum/5gzr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gzr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A1B0XTC8_ZIKV A0A1B0XTC8_ZIKV] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504]  Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Zika virus]]
[[Category: Gao GG]]
[[Category: Liu S]]
[[Category: Peng R]]
[[Category: Shi Y]]