View source for 5hch


==X-ray structure of a lectin-bound DNA duplex containing an unnatural phenanthrenyl pair==
<StructureSection load='5hch' size='340' side='right'caption='[[5hch]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5hch]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HCH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HCH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=61H:(1R)-1,4-ANHYDRO-2-DEOXY-5-O-[(S)-HYDROXY(OXIDO)-LAMBDA~5~-PHOSPHANYL]-1-PHENANTHREN-2-YL-D-ERYTHRO-PENTITOL'>61H</scene>, <scene name='pdbligand=61J:(6S)-2,6-ANHYDRO-1-DEOXY-6-(2-{[(S)-HYDROXY(OXIDO)-LAMBDA~5~-PHOSPHANYL]OXY}ETHYL)-D-GALACTITOL'>61J</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hch FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hch OCA], [https://pdbe.org/5hch PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hch RCSB], [https://www.ebi.ac.uk/pdbsum/5hch PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hch ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9HYN5_PSEAE Q9HYN5_PSEAE] 
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
DNA duplexes containing unnatural base-pair surrogates are attractive biomolecular nanomaterials with potentially beneficial photophysical or electronic properties. Herein we report the first X-ray structure of a duplex containing a phen-pair in the center of the double helix in a zipper like stacking arrangement.

X-ray structure of a lectin-bound DNA duplex containing an unnatural phenanthrenyl pair.,Roethlisberger P, Istrate A, Marcaida Lopez MJ, Visini R, Stocker A, Reymond JL, Leumann CJ Chem Commun (Camb). 2016 Feb 22. PMID:26898721<ref>PMID:26898721</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 5hch" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Synthetic construct]]
[[Category: Istrate A]]
[[Category: Leumann CJ]]
[[Category: Marcaida Lopez MJ]]
[[Category: Roethlisberger P]]
[[Category: Stocker A]]
[[Category: Visini R]]