View source for 5hnx


==Structural basis of backwards motion in kinesin-14: minus-end directed nKn664 in the nucleotide-free state==
<SX load='5hnx' size='340' side='right' viewer='molstar' caption='[[5hnx]], [[Resolution|resolution]] 6.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5hnx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HNX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HNX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TA1:TAXOL'>TA1</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hnx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hnx OCA], [https://pdbe.org/5hnx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hnx RCSB], [https://www.ebi.ac.uk/pdbsum/5hnx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hnx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

==See Also==
*[[Tubulin 3D Structures|Tubulin 3D Structures]]
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</SX>
[[Category: Bos taurus]]
[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Kikkawa M]]
[[Category: Nitta R]]
[[Category: Shigematsu H]]
[[Category: Shirouzu M]]
[[Category: Yokoyama T]]