View source for 5hpn


==A circularly permuted PduA forming an icosahedral cage==
<StructureSection load='5hpn' size='340' side='right'caption='[[5hpn]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5hpn]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HPN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.509&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hpn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hpn OCA], [https://pdbe.org/5hpn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hpn RCSB], [https://www.ebi.ac.uk/pdbsum/5hpn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hpn ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
We report the crystal structure of a novel 60-subunit dodecahedral cage that results from self-assembly of a re-engineered version of a natural protein (PduA) from the Pdu microcompartment shell. Biophysical data illustrate the dependence of assembly on solution conditions, opening up new applications in microcompartment studies and nanotechnology.

Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein.,Jorda J, Leibly DJ, Thompson MC, Yeates TO Chem Commun (Camb). 2016 Apr 11;52(28):5041-4. doi: 10.1039/c6cc00851h. Epub 2016, Mar 18. PMID:26988700<ref>PMID:26988700</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 5hpn" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Jorda J]]
[[Category: Leibly DJ]]
[[Category: Yeates TO]]