View source for 5huz


==Solution structure of coiled coil domain of myosin binding subunit of myosin light chain phosphatase==
<StructureSection load='5huz' size='340' side='right'caption='[[5huz]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5huz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2mxr 2mxr]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HUZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HUZ FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5huz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5huz OCA], [https://pdbe.org/5huz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5huz RCSB], [https://www.ebi.ac.uk/pdbsum/5huz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5huz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MYPT1_HUMAN MYPT1_HUMAN] Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.<ref>PMID:19245366</ref> <ref>PMID:18477460</ref> <ref>PMID:20354225</ref> 

==See Also==
*[[Protein phosphatase 3D structures|Protein phosphatase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Alper SL]]
[[Category: Anklin C]]
[[Category: Birrane G]]
[[Category: Pollak M]]
[[Category: Rigby AC]]
[[Category: Sharma AK]]