View source for 5i36


==Crystal structure of color device state A==
<StructureSection load='5i36' size='340' side='right'caption='[[5i36]], [[Resolution|resolution]] 5.12&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5i36]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I36 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5I36 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 5.123&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5i36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i36 OCA], [https://pdbe.org/5i36 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5i36 RCSB], [https://www.ebi.ac.uk/pdbsum/5i36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5i36 ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Structural DNA nanotechnology finds applications in numerous areas, but the construction of objects, 2D and 3D crystalline lattices and devices is prominent among them. Each of these components has been developed individually, and most of them have been combined in pairs. However, to date there are no reports of independent devices contained within 3D crystals. Here we report a three-state 3D device whereby we change the colour of the crystals by diffusing strands that contain dyes in or out of the crystals through the mother-liquor component of the system. Each colouring strand is designed to pair with an extended triangle strand by Watson-Crick base pairing. The arm that contains the dyes is quite flexible, but it is possible to establish the presence of the duplex proximal to the triangle by X-ray crystallography. We modelled the transition between the red and blue states through a simple kinetic model.

A device that operates within a self-assembled 3D DNA crystal.,Hao Y, Kristiansen M, Sha R, Birktoft JJ, Hernandez C, Mao C, Seeman NC Nat Chem. 2017 Aug;9(8):824-827. doi: 10.1038/nchem.2745. Epub 2017 Mar 14. PMID:28754940<ref>PMID:28754940</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 5i36" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Birktoft J]]
[[Category: Hao Y]]
[[Category: Kristiansen M]]
[[Category: Mao C]]
[[Category: Seeman NC]]
[[Category: Sha R]]