View source for 5jci


==Structure and catalytic mechanism of monodehydroascorbate reductase, MDHAR, from Oryza sativa L. japonica==
<StructureSection load='5jci' size='340' side='right'caption='[[5jci]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5jci]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa_Japonica_Group Oryza sativa Japonica Group]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JCI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JCI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jci OCA], [https://pdbe.org/5jci PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jci RCSB], [https://www.ebi.ac.uk/pdbsum/5jci PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jci ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MDAR3_ORYSJ MDAR3_ORYSJ] Catalyzes the conversion of monodehydroascorbate to ascorbate, oxidizing NADH in the process. Ascorbate is a major antioxidant against reactive oxygen species (ROS) and nitric oxide (NO) (PubMed:24376554, PubMed:27652777). Can use NADPH as electron donor, but possesses lower activity compared to NADH as electron donor (PubMed:27652777).<ref>PMID:24376554</ref> <ref>PMID:27652777</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Oryza sativa Japonica Group]]
[[Category: Kim HW]]
[[Category: Park AK]]