View source for 5jwj


==NMR solution structure of a thermophilic lysine methyl transferase from Sulfolobus islandicus==
<StructureSection load='5jwj' size='340' side='right'caption='[[5jwj]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5jwj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfolobus_islandicus_REY15A Sulfolobus islandicus REY15A]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JWJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JWJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jwj OCA], [https://pdbe.org/5jwj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jwj RCSB], [https://www.ebi.ac.uk/pdbsum/5jwj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jwj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KMT_SULIR KMT_SULIR] Catalyzes the methylation of lysine residues in target proteins, using S-adenosyl-L-methionine (SAM) as the methyl donor. Exhibits broad substrate specificity, being able to methylate the crenarchaeal chromatin protein Cren7 primarily at 'Lys-11', 'Lys-16' and 'Lys-31', as well as a number of recombinant Sulfolobus proteins in vitro. Methylates lysine residues in a rather sequence-independent manner.<ref>PMID:23086207</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Sulfolobus islandicus REY15A]]
[[Category: Schwarz-Linnet T]]
[[Category: She Q]]
[[Category: Stiefler-Jensen D]]
[[Category: Teilum K]]
[[Category: De Lichtenberg C]]