View source for 5jyg


==Cryo-EM structure of the MamK filament at 6.5 A==
<SX load='5jyg' size='340' side='right' viewer='molstar' caption='[[5jyg]], [[Resolution|resolution]] 6.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5jyg]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Magnetospirillum_magneticum_AMB-1 Magnetospirillum magneticum AMB-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JYG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JYG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jyg OCA], [https://pdbe.org/5jyg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jyg RCSB], [https://www.ebi.ac.uk/pdbsum/5jyg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jyg ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MAMK_MAGSA MAMK_MAGSA] Protein with ATPase activity which forms dynamic cytoplasmic filaments (probably with paralog MamK-like) that organize magnetosomes into long chains running parallel to the long axis of the cell (Probable) (PubMed:21883528, PubMed:28790202, PubMed:23204522, PubMed:24957623). Turnover of MamK filaments is probably promoted by MamK-like, which provides a monomer pool (PubMed:24957623). Forms twisted filaments in the presence of ATP or GTP (PubMed:20161777, PubMed:23204522, PubMed:27391173). Serves to close gaps between magnetosomes in the chain (PubMed:26884433). Interaction with MCP10 is involved in controlling the response to magnetic fields, possibly by controlling flagellar rotation (PubMed:20471399). Expression in E.coli yields a filament in the cell's longitudinal axis; the protein nucleates at several sites and one extremity of the filament is located at the cell pole (PubMed:17085581, PubMed:20161777).<ref>PMID:17085581</ref> <ref>PMID:20161777</ref> <ref>PMID:20471399</ref> <ref>PMID:21883528</ref> <ref>PMID:23204522</ref> <ref>PMID:24957623</ref> <ref>PMID:26884433</ref> <ref>PMID:27391173</ref> <ref>PMID:28790202</ref> <ref>PMID:16373532</ref> 
== References ==
<references/>
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</SX>
[[Category: Large Structures]]
[[Category: Magnetospirillum magneticum AMB-1]]
[[Category: Bergeron JRC]]
[[Category: Hutto R]]
[[Category: Kollman JM]]