View source for 5ko0


==Human Islet Amyloid Polypeptide Segment 15-FLVHSSNNFGA-25 Determined by MicroED==
<StructureSection load='5ko0' size='340' side='right'caption='[[5ko0]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5ko0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KO0 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron crystallography, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ko0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ko0 OCA], [https://pdbe.org/5ko0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ko0 RCSB], [https://www.ebi.ac.uk/pdbsum/5ko0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ko0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IAPP_HUMAN IAPP_HUMAN] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Cascio D]]
[[Category: Eisenberg DS]]
[[Category: Gonen T]]
[[Category: Hattne J]]
[[Category: Krotee PAL]]
[[Category: Nannenga BL]]
[[Category: Reyes FE]]
[[Category: Rodriguez JA]]
[[Category: Sawaya MR]]
[[Category: Shi D]]