View source for 5lj6


==Structure of Aggregatibacter actinomycetemcomitans MacB bound to ATPyS (P6522)==
<StructureSection load='5lj6' size='340' side='right'caption='[[5lj6]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5lj6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aggregatibacter_actinomycetemcomitans Aggregatibacter actinomycetemcomitans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LJ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LJ6 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lj6 OCA], [https://pdbe.org/5lj6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lj6 RCSB], [https://www.ebi.ac.uk/pdbsum/5lj6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lj6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MACB_AGGAC MACB_AGGAC] Part of the tripartite efflux system MacAB-TdeA. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.<ref>PMID:19432486</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Aggregatibacter actinomycetemcomitans]]
[[Category: Large Structures]]
[[Category: Crow A]]