View source for 5lkd


==Crystal structure of the Xi glutathione transferase ECM4 from Saccharomyces cerevisiae in complex with glutathione==
<StructureSection load='5lkd' size='340' side='right'caption='[[5lkd]], [[Resolution|resolution]] 1.68&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5lkd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LKD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LKD FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.68&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lkd OCA], [https://pdbe.org/5lkd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lkd RCSB], [https://www.ebi.ac.uk/pdbsum/5lkd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lkd ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GTO2_YEAST GTO2_YEAST] Active as '1-Cys' thiol transferase against beta-hydroxyethyl disulfide (HED), as dehydroascorbate reductase and as dimethylarsinic acid reductase, while not active against the standard GST substrate 1-chloro-2,4-dinitrobenzene (CDNB). May be involved in cell wall organization and biogenesis.<ref>PMID:16709151</ref> 

==See Also==
*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Didierjean C]]
[[Category: Favier F]]
[[Category: Gelhaye E]]
[[Category: Girardet JM]]
[[Category: Hecker A]]
[[Category: Morel-Rouhier M]]
[[Category: Schwartz M]]