View source for 5msq


==Structure of the A domain of carboxylic acid reductase (CAR) from Nocardia iowensis in complex with AMP and iodide==
<StructureSection load='5msq' size='340' side='right'caption='[[5msq]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5msq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nocardia_iowensis Nocardia iowensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MSQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MSQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5msq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5msq OCA], [https://pdbe.org/5msq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5msq RCSB], [https://www.ebi.ac.uk/pdbsum/5msq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5msq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CAR_NOCIO CAR_NOCIO] Catalyzes the reduction of a very wide range of aliphatic carboxylic acids as well as many aryl carboxylic acids into their corresponding aldehydes, by using ATP for energy to drive the reaction. Aryl carboxylic acid substrates include substituted benzoic acids, phenyl-substituted aliphatic acids, heterocyclic carboxylic acids, and polyaromatic ring carboxylic acids. Cannot reduce benzaldehyde to benzyl alcohol.<ref>PMID:15006821</ref> <ref>PMID:17102130</ref> <ref>PMID:9171390</ref> <ref>PMID:9171390</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Nocardia iowensis]]
[[Category: Dunstan MS]]
[[Category: Leys D]]