View source for 5nhs


==The crystal structure of Xanthomonas albilineans N5, N10-methylenetetrahydrofolate dehydrogenase-cyclohydrolase (FolD)==
<StructureSection load='5nhs' size='340' side='right'caption='[[5nhs]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5nhs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanthomonas_albilineans_GPE_PC73 Xanthomonas albilineans GPE PC73]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NHS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.11&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nhs OCA], [https://pdbe.org/5nhs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nhs RCSB], [https://www.ebi.ac.uk/pdbsum/5nhs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nhs ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/D2UAL4_XANAP D2UAL4_XANAP] Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.[HAMAP-Rule:MF_01576][SAAS:SAAS00730939]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Xanthomonas albilineans GPE PC73]]
[[Category: Bueno RV]]
[[Category: Guido RVC]]
[[Category: Lima GMA]]
[[Category: Maluf FV]]
[[Category: Oliveira AA]]