View source for 5nqs


==Structure of the Arabidopsis Thaliana TOPLESS N-terminal domain==
<StructureSection load='5nqs' size='340' side='right'caption='[[5nqs]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5nqs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NQS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NQS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.61&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nqs OCA], [https://pdbe.org/5nqs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nqs RCSB], [https://www.ebi.ac.uk/pdbsum/5nqs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nqs ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TPL_ARATH TPL_ARATH] Transcriptional corepressor. May repress the expression of root-promoting genes in the top half of the embryo to allow proper differentiation of the shoot pole during the transition stage of embryogenesis. Regulates the expression of PLT1 and PLT2. Negative regulator of jasmonate responses. Negative regulator of auxin responses. Negative regulator of multiple floral organ identity genes (PubMed:23034631). Required for ovule development (PubMed:25378179).<ref>PMID:16763149</ref> <ref>PMID:18258861</ref> <ref>PMID:20190735</ref> <ref>PMID:20360743</ref> <ref>PMID:23034631</ref> <ref>PMID:25378179</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Arevalillo MR]]
[[Category: Dumas R]]
[[Category: Nanao MH]]
[[Category: Parcy F]]
[[Category: Vinos-Poyo T]]