View source for 5nxd


==LIM Domain Kinase 2 (LIMK2) In Complex With TH-300==
<StructureSection load='5nxd' size='340' side='right'caption='[[5nxd]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5nxd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NXD FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9D8:4-[(3-CHLOROPHENYL)SULFAMOYL]-~{N}-(PHENYLMETHYL)-~{N}-PROPYL-BENZAMIDE'>9D8</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nxd OCA], [https://pdbe.org/5nxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nxd RCSB], [https://www.ebi.ac.uk/pdbsum/5nxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nxd ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LIMK2_HUMAN LIMK2_HUMAN] Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro.<ref>PMID:10436159</ref> <ref>PMID:11018042</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Bountra C]]
[[Category: Bullock AN]]
[[Category: Burgess-Brown N]]
[[Category: Edwards AM]]
[[Category: Hanke T]]
[[Category: Knapp S]]
[[Category: Mathea S]]
[[Category: Newman JA]]
[[Category: Oerum S]]
[[Category: Salah E]]
[[Category: Wang D]]
[[Category: Von Delft F]]