View source for 5ods


==Structure of a phosphoprotein-protein complex==
<StructureSection load='5ods' size='340' side='right'caption='[[5ods]], [[Resolution|resolution]] 3.09&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5ods]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ODS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ODS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.09&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ods FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ods OCA], [https://pdbe.org/5ods PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ods RCSB], [https://www.ebi.ac.uk/pdbsum/5ods PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ods ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CLH1_MOUSE CLH1_MOUSE] Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension. Plays a role in early autophagosome formation.[UniProtKB:P11442][UniProtKB:Q00610]

==See Also==
*[[Clathrin 3D structures|Clathrin 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Bayliss R]]
[[Category: Mukherjee M]]