View source for 5qtq


==PanDDA analysis group deposition -- Crystal Structure of NUDT5 in complex with FS-1169==
<StructureSection load='5qtq' size='340' side='right'caption='[[5qtq]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5qtq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QTQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QTQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PWM:5-fluoroquinazolin-4(3H)-one'>PWM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qtq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qtq OCA], [https://pdbe.org/5qtq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qtq RCSB], [https://www.ebi.ac.uk/pdbsum/5qtq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qtq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NUDT5_HUMAN NUDT5_HUMAN] Hydrolyzes with similar activities ADP-ribose ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity.<ref>PMID:17052728</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Bountra C]]
[[Category: Burgess-Brown N]]
[[Category: Dubianok Y]]
[[Category: Edwards A]]
[[Category: Kovacs H]]
[[Category: Krojer T]]
[[Category: Moriaud F]]
[[Category: Strain-Damerell C]]
[[Category: Wright N]]
[[Category: Von Delft F]]