View source for 5syf


==High-resolution cryo-EM reconstruction of Taxol-stabilized microtubule==
<SX load='5syf' size='340' side='right' viewer='molstar' caption='[[5syf]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5syf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SYF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SYF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TA1:TAXOL'>TA1</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5syf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5syf OCA], [https://pdbe.org/5syf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5syf RCSB], [https://www.ebi.ac.uk/pdbsum/5syf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5syf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TBA1B_PIG TBA1B_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

==See Also==
*[[Tubulin 3D Structures|Tubulin 3D Structures]]
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</SX>
[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Kellogg EH]]
[[Category: Nogales E]]