View source for 5tcm


==First Bromodomain from Leishmania donovani LdBPK.091320 complexed with BI-2536==
<StructureSection load='5tcm' size='340' side='right'caption='[[5tcm]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5tcm]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_donovani_BPK282A1 Leishmania donovani BPK282A1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TCM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TCM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=R78:4-{[(7R)-8-CYCLOPENTYL-7-ETHYL-5-METHYL-6-OXO-5,6,7,8-TETRAHYDROPTERIDIN-2-YL]AMINO}-3-METHOXY-N-(1-METHYLPIPERIDIN-4-YL)BENZAMIDE'>R78</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tcm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tcm OCA], [https://pdbe.org/5tcm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tcm RCSB], [https://www.ebi.ac.uk/pdbsum/5tcm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tcm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A3Q8I8I6_LEIDO A0A3Q8I8I6_LEIDO] 
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Leishmania donovani BPK282A1]]
[[Category: Arrowsmith CH]]
[[Category: Bountra C]]
[[Category: Dong A]]
[[Category: Edwards AM]]
[[Category: Hou CFD]]
[[Category: Hui R]]
[[Category: Lin YH]]
[[Category: Loppnau P]]
[[Category: Walker JR]]