View source for 5tzk


==Crystal structure of S. aureus TarS 1-349 in complex with UDP==
<StructureSection load='5tzk' size='340' side='right'caption='[[5tzk]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5tzk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TZK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TZK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.22&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tzk OCA], [https://pdbe.org/5tzk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tzk RCSB], [https://www.ebi.ac.uk/pdbsum/5tzk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tzk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TARS_STAAM TARS_STAAM] Attaches beta-O-GlcNAc (beta-O-N-acetyl-D-glucosamine) residues to the C4 position of poly(RboP)-wall teichoic acids (WTAs). Mediates beta-lactam resistance in methicillin resistant Staphylococcus aureus (MRSA) strains.<ref>PMID:27973583</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: King DT]]
[[Category: Sobhanifar S]]
[[Category: Strynadka NC]]
[[Category: Worrall LJ]]