View source for 5ufl


==Crystal structure of a CIP2A core domain==
<StructureSection load='5ufl' size='340' side='right'caption='[[5ufl]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5ufl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UFL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ufl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ufl OCA], [https://pdbe.org/5ufl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ufl RCSB], [https://www.ebi.ac.uk/pdbsum/5ufl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ufl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CIP2A_HUMAN CIP2A_HUMAN] Oncoprotein that inhibits PP2A and stabilizes MYC in human malignancies. Promotes anchorage-independent cell growth and tumor formation.<ref>PMID:17632056</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Rao Z]]
[[Category: Wang J]]
[[Category: Wang Z]]
[[Category: Xu W]]