View source for 5uw8


==Structure of E. coli MCE protein MlaD, core MCE domain==
<StructureSection load='5uw8' size='340' side='right'caption='[[5uw8]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5uw8]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O157:H7 Escherichia coli O157:H7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UW8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UW8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5uw8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uw8 OCA], [https://pdbe.org/5uw8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5uw8 RCSB], [https://www.ebi.ac.uk/pdbsum/5uw8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5uw8 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MLAD_ECO57 MLAD_ECO57] Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane.[UniProtKB:P64604]
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</StructureSection>
[[Category: Escherichia coli O157:H7]]
[[Category: Large Structures]]
[[Category: Bhabha G]]
[[Category: Ekiert DC]]