View source for 5vc9


==Zinc finger of human CXXC4 in complex with CpG DNA==
<StructureSection load='5vc9' size='340' side='right'caption='[[5vc9]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5vc9]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VC9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VC9 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vc9 OCA], [https://pdbe.org/5vc9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vc9 RCSB], [https://www.ebi.ac.uk/pdbsum/5vc9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vc9 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CXXC4_HUMAN CXXC4_HUMAN] Acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Arrowsmith CH]]
[[Category: Bountra C]]
[[Category: Edwards AM]]
[[Category: Liu K]]
[[Category: Min J]]
[[Category: Tempel W]]
[[Category: Walker JR]]
[[Category: Xu C]]