View source for 5vym


==Crystal structure of beta-galactosidase from Bifidobacterium adolescentis==
<StructureSection load='5vym' size='340' side='right'caption='[[5vym]], [[Resolution|resolution]] 2.46&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5vym]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bifidobacterium_adolescentis_ATCC_15703 Bifidobacterium adolescentis ATCC 15703]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VYM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.456&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vym OCA], [https://pdbe.org/5vym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vym RCSB], [https://www.ebi.ac.uk/pdbsum/5vym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vym ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BGAL_BIFAA BGAL_BIFAA] Involved in the hydrolysis of transgalactooligosaccharides (TOS). Highly active towards Gal(beta1-4)Gal and Gal(beta1-4)-Gal-containing oligosaccharides. Low activity towards Gal(beta1-3)Gal, lactose and Gal(beta1-3)GalOMe. No activity towards Gal(beta1-6)Gal, Gal(beta1-4)Man, Gal(alpha1-4)Gal, Gal(alpha1-3)Gal(beta1-4)Gal, lactulose, 3'fucosyllactose, lacto-N-fucopentaose I, lacto-N-fucopentaose II, cellobiose, maltose or sucrose. No transglycosylation activity is found at high substrate concentrations (100 mg/ml) and only low transglycosylation activity at lower substrate concentrations (10 mg/ml).<ref>PMID:10742215</ref> <ref>PMID:15480628</ref> 

==See Also==
*[[Galactosidase 3D structures|Galactosidase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bifidobacterium adolescentis ATCC 15703]]
[[Category: Large Structures]]
[[Category: Chang C]]
[[Category: Cuff M]]
[[Category: Endres M]]
[[Category: Joachimiak A]]
[[Category: Tesar C]]