View source for 5wuq


==Crystal structure of SigW in complex with its anti-sigma RsiW, a zinc binding form==
<StructureSection load='5wuq' size='340' side='right'caption='[[5wuq]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5wuq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WUQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WUQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wuq OCA], [https://pdbe.org/5wuq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wuq RCSB], [https://www.ebi.ac.uk/pdbsum/5wuq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wuq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SIGW_BACSU SIGW_BACSU] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor (RsiW for this protein) until released by regulated membrane proteolysis. Sigma-W controls genes involved in transport processes and detoxification.<ref>PMID:12073657</ref> <ref>PMID:21685450</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis subsp. subtilis str. 168]]
[[Category: Large Structures]]
[[Category: Devkota SR]]
[[Category: Ha SC]]
[[Category: Kim DY]]
[[Category: Kwon E]]