View source for 5wwn


==Crystal structure of Tsr1==
<StructureSection load='5wwn' size='340' side='right'caption='[[5wwn]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5wwn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WWN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WWN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.805&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wwn OCA], [https://pdbe.org/5wwn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wwn RCSB], [https://www.ebi.ac.uk/pdbsum/5wwn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wwn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TSR1_YEAST TSR1_YEAST] Required for 40S ribosomal subunit synthesis. Required for normal export of the pre-40S particles from the nucleus to the cytoplasm. Its subcellular location and association with pre-40S subunitshifts from mixed cytoplasm/nucleus to all nuclear in RPS19 disruptions, suggesting it acts after the ribosomal protein.<ref>PMID:11565749</ref> <ref>PMID:12628929</ref> <ref>PMID:15167894</ref> <ref>PMID:16159874</ref> 

==See Also==
*[[Ribosome biogenesis protein 3D structures|Ribosome biogenesis protein 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Wang B]]
[[Category: Ye K]]