View source for 5xal


==Y99F mutant of Thermus thermophilus HB8 thymidylate kinase==
<StructureSection load='5xal' size='340' side='right'caption='[[5xal]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5xal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XAL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xal OCA], [https://pdbe.org/5xal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xal RCSB], [https://www.ebi.ac.uk/pdbsum/5xal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xal ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KTHY_THET8 KTHY_THET8] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

==See Also==
*[[Thymidylate kinase 3D structures|Thymidylate kinase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermus thermophilus HB8]]
[[Category: Chaudhary SK]]
[[Category: Jeyakanthan J]]
[[Category: Sekar K]]