View source for 5xf0


==Solution structure of the IgI domain of CD147==
<StructureSection load='5xf0' size='340' side='right'caption='[[5xf0]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5xf0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XF0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XF0 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xf0 OCA], [https://pdbe.org/5xf0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xf0 RCSB], [https://www.ebi.ac.uk/pdbsum/5xf0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xf0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BASI_HUMAN BASI_HUMAN] Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.<ref>PMID:17127621</ref> 

==See Also==
*[[3D structures of basigin|3D structures of basigin]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Jin SJ]]
[[Category: Xia B]]