View source for 5xuv


==Crystal structure of DNA duplex containing 4-thiothymine-2Ag(I)-4-thiothymine base pairs==
<StructureSection load='5xuv' size='340' side='right'caption='[[5xuv]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5xuv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XUV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XUV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8RO:[(2~{R},3~{S},5~{R})-5-(5-methyl-2-oxidanylidene-7-thia-1,3-diazabicyclo[4.1.0]hept-5-en-3-yl)-3-oxidanyl-oxolan-2-yl]methyl+dihydrogen+phosphite'>8RO</scene>, <scene name='pdbligand=AG:SILVER+ION'>AG</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xuv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xuv OCA], [https://pdbe.org/5xuv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xuv RCSB], [https://www.ebi.ac.uk/pdbsum/5xuv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xuv ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Herein, we determined a high-resolution crystal structure of a B-form DNA duplex containing consecutive dinuclear metal ion-mediated base pairs, namely, 4-thiothymine-2Ag(i)-4-thiothymine (S-2Ag(i)-S), and four Ag(i) ions form a rectangular network and the distances between the Ag(i) ions are 2.8-3.2 A, which may indicate the existence of metallophilic attractions.

Crystal structure of a DNA duplex containing four Ag(i) ions in consecutive dinuclear Ag(i)-mediated base pairs: 4-thiothymine-2Ag(i)-4-thiothymine.,Kondo J, Sugawara T, Saneyoshi H, Ono A Chem Commun (Camb). 2017 Aug 22;53(86):11747-11750. doi: 10.1039/c7cc06153f. PMID:28991300<ref>PMID:28991300</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 5xuv" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Kondo J]]
[[Category: Ono A]]
[[Category: Saneyoshi H]]
[[Category: Sugawara T]]