View source for 5zb1


==Monomeric crystal structure of orf57 from KSHV==
<StructureSection load='5zb1' size='340' side='right'caption='[[5zb1]], [[Resolution|resolution]] 3.06&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5zb1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_8 Human gammaherpesvirus 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZB1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZB1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.061&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zb1 OCA], [https://pdbe.org/5zb1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zb1 RCSB], [https://www.ebi.ac.uk/pdbsum/5zb1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zb1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ICP27_HHV8P ICP27_HHV8P] Early protein that promotes the accumulation and nuclear export of viral intronless RNA transcripts by interacting with mRNAs and cellular export proteins. Probably acts as a viral splicing factor that regulates viral RNA splicing. Functions as a multifunctional regulator of the expression of viral lytic genes.<ref>PMID:15155762</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Human gammaherpesvirus 8]]
[[Category: Large Structures]]
[[Category: Dong YH]]
[[Category: Gao ZQ]]
[[Category: Lan K]]
[[Category: Yuan F]]