View source for 5zsy


==RBM10-RRM2 domain and its lung cancer related mutant==
<StructureSection load='5zsy' size='340' side='right'caption='[[5zsy]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5zsy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZSY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZSY FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zsy OCA], [https://pdbe.org/5zsy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zsy RCSB], [https://www.ebi.ac.uk/pdbsum/5zsy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zsy ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN] TARP syndrome. TARP syndrome (TARPS) [MIM:[https://omim.org/entry/311900 311900]: A disorder characterized by the Robin sequence (micrognathia, glossoptosis and cleft palate), talipes equinovarus and cardiac defects. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:20451169</ref> 
== Function ==
[https://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN] May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity).<ref>PMID:18315527</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Qin H]]