View source for 6byx


==Complex structure of LOR107 mutant (R259N) with tetrasaccharide substrate==
<StructureSection load='6byx' size='340' side='right'caption='[[6byx]], [[Resolution|resolution]] 2.21&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6byx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Alteromonas_sp._LOR Alteromonas sp. LOR]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BYX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.208&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=83Y:6-DEOXY-3-O-SULFO-ALPHA-L-MANNOPYRANOSE'>83Y</scene>, <scene name='pdbligand=BDP:BETA-D-GLUCOPYRANURONIC+ACID'>BDP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GCD:4,5-DEHYDRO-D-GLUCURONIC+ACID'>GCD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6byx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6byx OCA], [https://pdbe.org/6byx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6byx RCSB], [https://www.ebi.ac.uk/pdbsum/6byx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6byx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/UL24S_ALTSL UL24S_ALTSL] Ulvan lyase involved in ulvan degradation. Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl). Ulvan lyase catalyzes preferentially the endolytic cleavage of the glycosidic bond between Rha3S and the uronic acid GlcA, but not IduA, producing oligosaccharides that have unsaturated 4-deoxy-L-threo-hex-4-enopyranosiduronic acid (deltaUA) at the non-reducing end. The most abundant end products in the degradation of the ulvan polysaccharide were deltaUA-Rha3S disaccharides and deltaUA-Rha3S-IduA-Rha3S and deltaUA-Rha3S-Xyl-Rha3S tetrasaccharides.<ref>PMID:26763234</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Alteromonas sp. LOR]]
[[Category: Large Structures]]
[[Category: Cygler M]]
[[Category: Ulaganathan T]]