View source for 6c78


==Substrate Binding Induces Conformational Changes In A Class A Beta Lactamase That Primes It For Catalysis==
<StructureSection load='6c78' size='340' side='right'caption='[[6c78]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6c78]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C78 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6C78 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Neutron Diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DOD:DEUTERATED+WATER'>DOD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6c78 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c78 OCA], [https://pdbe.org/6c78 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6c78 RCSB], [https://www.ebi.ac.uk/pdbsum/6c78 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6c78 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BLT1_ECOLX BLT1_ECOLX] Has strong cefotaxime-hydrolyzing activity.

==See Also==
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Coates L]]
[[Category: Cooper SJ]]
[[Category: Ginell SL]]
[[Category: Langan PS]]
[[Category: Parks JM]]
[[Category: Vandavasi VG]]
[[Category: Weiss KL]]