View source for 6ca0


==Cryo-EM structure of E. coli RNAP sigma70 open complex==
<SX load='6ca0' size='340' side='right' viewer='molstar' caption='[[6ca0]], [[Resolution|resolution]] 5.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6ca0]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CA0 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 5.75&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ca0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ca0 OCA], [https://pdbe.org/6ca0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ca0 RCSB], [https://www.ebi.ac.uk/pdbsum/6ca0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ca0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059]

==See Also==
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
*[[Sigma factor 3D structures|Sigma factor 3D structures]]
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</SX>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Jiang W]]
[[Category: Li K]]
[[Category: Murakami KS]]
[[Category: Narayanan A]]
[[Category: Qayyum MZ]]
[[Category: Vago F]]
[[Category: Yernool D]]