View source for 6cui


==Solution structure of the Extraterminal (ET) Domain of BRD2==
<StructureSection load='6cui' size='340' side='right'caption='[[6cui]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6cui]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CUI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CUI FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cui OCA], [https://pdbe.org/6cui PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cui RCSB], [https://www.ebi.ac.uk/pdbsum/6cui PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cui ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref> 

==See Also==
*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Filippakopoulos P]]
[[Category: Houliston S]]
[[Category: Lemak A]]
[[Category: Picaud S]]