View source for 6dxq


==Crystal structure of the LigJ Hydratase product complex with 4-carboxy-4-hydroxy-2-oxoadipate==
<StructureSection load='6dxq' size='340' side='right'caption='[[6dxq]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6dxq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sphingobium_sp._SYK-6 Sphingobium sp. SYK-6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DXQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DXQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.02&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7QD:(2S)-2-hydroxy-4-oxobutane-1,2,4-tricarboxylic+acid'>7QD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dxq OCA], [https://pdbe.org/6dxq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dxq RCSB], [https://www.ebi.ac.uk/pdbsum/6dxq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dxq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LIGJ_SPHSK LIGJ_SPHSK] Contributes to the degradation of lignin at the level of the protocatechuate 4,5-cleavage pathway. Catalyzes the hydration of the double bond of (3Z)-2-keto-4-carboxy-3-hexenedioate (KCH) to (4S)-4-carboxy-4-hydroxy-2-oxoadipate (CHA, also named (2S)-2-hydroxy-4-oxobutane-1,2,4-tricarboxylate) (PubMed:29658701, PubMed:30207699). Is involved in the catabolism of both vanillate and syringate (PubMed:11092855).<ref>PMID:11092855</ref> <ref>PMID:29658701</ref> <ref>PMID:30207699</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Sphingobium sp. SYK-6]]
[[Category: Mabanglo MF]]
[[Category: Raushel FM]]