View source for 6dzg


==Crystal structure of polyphosphate kinase 2 class I (SMc02148) in complex with ADP==
<StructureSection load='6dzg' size='340' side='right'caption='[[6dzg]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6dzg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sinorhizobium_meliloti_1021 Sinorhizobium meliloti 1021]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DZG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DZG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.87&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dzg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dzg OCA], [https://pdbe.org/6dzg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dzg RCSB], [https://www.ebi.ac.uk/pdbsum/6dzg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dzg ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PK21A_RHIME PK21A_RHIME] Uses inorganic polyphosphate (polyP) as a donor to convert ADP to ATP. Can also convert GDP to GTP, with lower efficiency. Cannot dephosphorylate ATP in the presence of polyP.<ref>PMID:19001261</ref> 

==See Also==
*[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Sinorhizobium meliloti 1021]]
[[Category: Joachimiak A]]
[[Category: Nocek B]]
[[Category: Ruszkowski M]]