View source for 6eld


==Crystal structure of TIA-1 RRM1 in complex with U1C==
<StructureSection load='6eld' size='340' side='right'caption='[[6eld]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6eld]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ELD OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6ELD FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6eld FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6eld OCA], [http://pdbe.org/6eld PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6eld RCSB], [http://www.ebi.ac.uk/pdbsum/6eld PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6eld ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/TIA1_HUMAN TIA1_HUMAN]] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis. 
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</StructureSection>
[[Category: Large Structures]]
[[Category: Jagtap, P K.A]]
[[Category: Sattler, M]]
[[Category: Protein-rna interaction]]
[[Category: Rna binding protein]]
[[Category: Rrm domain]]