View source for 6fca


==Catalytic subunit HisG from Psychrobacter arcticus ATP phosphoribosyltransferase (HisZG ATPPRT) in complex with PRPP==
<StructureSection load='6fca' size='340' side='right' caption='[[6fca]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6fca]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FCA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FCA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC+ACID'>PRP</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ATP_phosphoribosyltransferase ATP phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.17 2.4.2.17] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fca OCA], [http://pdbe.org/6fca PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fca RCSB], [http://www.ebi.ac.uk/pdbsum/6fca PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fca ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/HIS1_PSYA2 HIS1_PSYA2]] Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. 
__TOC__
</StructureSection>
[[Category: ATP phosphoribosyltransferase]]
[[Category: Alphey, M S]]
[[Category: Czekster, C M]]
[[Category: Fisher, G]]
[[Category: Ge, Y]]
[[Category: Naismith, J H]]
[[Category: Silva, R G.da]]
[[Category: Catalytic]]
[[Category: Cold-adapted]]
[[Category: Hisg]]
[[Category: Phosphoribosyltransferase]]
[[Category: Transferase]]