View source for 6fpz


==Inter-alpha-inhibitor heavy chain 1, D298A==
<StructureSection load='6fpz' size='340' side='right'caption='[[6fpz]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6fpz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FPZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FPZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6fpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fpz OCA], [https://pdbe.org/6fpz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6fpz RCSB], [https://www.ebi.ac.uk/pdbsum/6fpz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6fpz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ITIH1_HUMAN ITIH1_HUMAN] May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.  Contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Briggs DC]]
[[Category: Day AJ]]