View source for 6fzs


==Crystal structure of Smad5-MH1 bound to the GGCGC site.==
<StructureSection load='6fzs' size='340' side='right'caption='[[6fzs]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6fzs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FZS OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6FZS FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SMAD5, MADH5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6fzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fzs OCA], [http://pdbe.org/6fzs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fzs RCSB], [http://www.ebi.ac.uk/pdbsum/6fzs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fzs ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/SMAD5_HUMAN SMAD5_HUMAN]] Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). 
__TOC__
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Kaczmarska, Z]]
[[Category: Macias, M J]]
[[Category: Marquez, J A]]
[[Category: Dna complex]]
[[Category: Smad]]
[[Category: Transcription]]
[[Category: Transcription factor]]