View source for 6g57


==Structure of the H1 domain of human KCTD8==
<StructureSection load='6g57' size='340' side='right'caption='[[6g57]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6g57]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G57 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6G57 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6g57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g57 OCA], [https://pdbe.org/6g57 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6g57 RCSB], [https://www.ebi.ac.uk/pdbsum/6g57 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6g57 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KCTD8_HUMAN KCTD8_HUMAN] Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Bountra C]]
[[Category: Bufton JC]]
[[Category: Bullock AN]]
[[Category: Burgess-Brown NA]]
[[Category: Edwards AM]]
[[Category: Fairhead M]]
[[Category: Pinkas DM]]
[[Category: Strain-Damerell CM]]
[[Category: Von Delft F]]