View source for 6gbn


==Crystal structure of S-adenosyl-L-homocysteine hydrolase from Cytophaga hutchinsonii in complex with adenosine==
<StructureSection load='6gbn' size='340' side='right' caption='[[6gbn]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6gbn]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GBN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GBN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylhomocysteinase Adenosylhomocysteinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.3.1.1 3.3.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gbn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gbn OCA], [http://pdbe.org/6gbn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gbn RCSB], [http://www.ebi.ac.uk/pdbsum/6gbn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gbn ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/Q11XG9_CYTH3 Q11XG9_CYTH3]] May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.[HAMAP-Rule:MF_00563] 
__TOC__
</StructureSection>
[[Category: Adenosylhomocysteinase]]
[[Category: Brzezinski, K]]
[[Category: Czyrko, J]]
[[Category: Jaskolski, M]]
[[Category: Cellular methylation]]
[[Category: Hydrolase]]
[[Category: Regulation of sam-dependent methylation reaction]]