View source for 6gru


==Crystal structure of human NUDT5==
<StructureSection load='6gru' size='340' side='right' caption='[[6gru]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6gru]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GRU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GRU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gru OCA], [http://pdbe.org/6gru PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gru RCSB], [http://www.ebi.ac.uk/pdbsum/6gru PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gru ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/NUDT5_HUMAN NUDT5_HUMAN]] Hydrolyzes with similar activities ADP-ribose ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity.<ref>PMID:17052728</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Burgess-Brown, N]]
[[Category: Collins, P]]
[[Category: Delft, F von]]
[[Category: Dubianok, Y]]
[[Category: Edwards, A]]
[[Category: Elkins, J]]
[[Category: Fairhead, M]]
[[Category: Huber, K]]
[[Category: Krojer, T]]
[[Category: MacLean, E]]
[[Category: Structural genomic]]
[[Category: Saez, L Diaz]]
[[Category: Strain-Damerell, C]]
[[Category: Hydrolase]]
[[Category: Nudix domain]]
[[Category: Sgc]]