View source for 6ip2


==NSF-D1D2 part in the whole 20S complex==
<SX load='6ip2' size='340' side='right' viewer='molstar' caption='[[6ip2]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6ip2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Cricetulus_griseus Cricetulus griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IP2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IP2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ip2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ip2 OCA], [https://pdbe.org/6ip2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ip2 RCSB], [https://www.ebi.ac.uk/pdbsum/6ip2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ip2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NSF_CRIGR NSF_CRIGR] Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling.
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[[Category: Cricetulus griseus]]
[[Category: Large Structures]]
[[Category: Fan F]]
[[Category: Huang X]]
[[Category: Sui SF]]
[[Category: Sun S]]
[[Category: Wang X]]
[[Category: Zhou Q]]