View source for 6izi


==Crystal structure of E. coli peptide deformylase and methionine aminopeptidase fitted into the cryo-EM density map of the complex==
<SX load='6izi' size='340' side='right' viewer='molstar' caption='[[6izi]], [[Resolution|resolution]] 11.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6izi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IZI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IZI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 11.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6izi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6izi OCA], [https://pdbe.org/6izi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6izi RCSB], [https://www.ebi.ac.uk/pdbsum/6izi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6izi ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DEF_ECOLI DEF_ECOLI] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]

==See Also==
*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
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</SX>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Akbar S]]
[[Category: Bhakta S]]
[[Category: Sengupta J]]