View source for 6jbp


==Structure of MP-4 from Mucuna pruriens at 2.22 Angstroms==
<StructureSection load='6jbp' size='340' side='right'caption='[[6jbp]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6jbp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mucuna_pruriens Mucuna pruriens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JBP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JBP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.217&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jbp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jbp OCA], [https://pdbe.org/6jbp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jbp RCSB], [https://www.ebi.ac.uk/pdbsum/6jbp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jbp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A371E4L6_MUCPR A0A371E4L6_MUCPR] 
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The structure of the MP-4 protein was previously determined at a resolution of 2.8 A. Owing to the unavailability of gene-sequence information at the time, the side-chain assignment was carried out on the basis of a partial sequence available through Edman degradation, sequence homology to orthologs and electron density. The structure of MP-4 has now been determined at a higher resolution (2.22 A) in another space group and all of the structural inferences that were presented in the previous report of the structure were validated. In addition, the present data allowed an improved assignment of side chains and enabled further analysis of the MP-4 structure, and the accuracy of the assignment was confirmed by the recently available gene sequence. The study reinforces the traditional concept that conservative interpretations of relatively low-resolution structures remain correct even with the availability of high-resolution data.

The structure of MP-4 from Mucuna pruriens at 2.22 A resolution.,Jain A, Kumar A, Shikhi M, Kumar A, Nair DT, Salunke DM Acta Crystallogr F Struct Biol Commun. 2020 Feb 1;76(Pt 2):47-57. doi:, 10.1107/S2053230X20000199. Epub 2020 Feb 3. PMID:32039885<ref>PMID:32039885</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 6jbp" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mucuna pruriens]]
[[Category: Jain A]]
[[Category: Kumar A]]
[[Category: Nair DT]]
[[Category: Salunke DM]]
[[Category: Shikhi M]]