View source for 6jfe


==K2U bound crystal structure of class I type b peptide deformylase from Pseudomonas aeruginosa==
<StructureSection load='6jfe' size='340' side='right'caption='[[6jfe]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6jfe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JFE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JFE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K3U:S-(2-oxo-2-phenylethyl)+(2R)-2-benzyl-4,4,4-trifluorobutanethioate'>K3U</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jfe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jfe OCA], [https://pdbe.org/6jfe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jfe RCSB], [https://www.ebi.ac.uk/pdbsum/6jfe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jfe ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A071LDC0_PSEAI A0A071LDC0_PSEAI] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Ho TH]]
[[Category: Kang LW]]
[[Category: Lee IH]]