View source for 6jfr


==K3U bound crystal structure of class II peptide deformylase from methicillin resistant Staphylococcus aureus==
<StructureSection load='6jfr' size='340' side='right'caption='[[6jfr]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6jfr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JFR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JFR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K3U:S-(2-oxo-2-phenylethyl)+(2R)-2-benzyl-4,4,4-trifluorobutanethioate'>K3U</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jfr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jfr OCA], [https://pdbe.org/6jfr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jfr RCSB], [https://www.ebi.ac.uk/pdbsum/6jfr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jfr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DEF_STAAU DEF_STAAU] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).[HAMAP-Rule:MF_00163]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Ho TH]]
[[Category: Kang LW]]
[[Category: Lee IH]]